AESTDTC before RFICDTC

AESTDTC before RFICDTC

Looks as you have a data quality error ...
How can one have an AE before informed consent was signed? Medication should normally not have started before the informed consent was signed, so either it is not an AE or you have a heavy protocol violation ...
Better document this in your reviewers guide ...

AESTDTC before RFICDTC

Indeed, this is a data issue. This will go into the RG, of course. It is listed as an AE before first Treatment.

But still I would expect the cdisc checker to give me an error in such a case.

Thank you!

AESTDTC before RFICDTC

Does the SDTM-IG actually state that this is a rule?

If not, than it is not a rule, and we should not invent new ones.

For your own company, you can of course always add such a "company-specific rule".
After all, OpenCDISC is open source.

P.S. You should not use the term "CDISC Checker", that is something else ...