1777 Sentry Parkway West
Building 17, Suite 405
Blue Bell, PA 19422
+1 (888) 507-2270
MethodDef Element Type
Forums: Define.xml
MethodDef Element Type
"Imputation" is typical for ADaM submissions. It should essentially not appear in SDTM or SEND submissions, as imputations are not allowed there.
This is one of the things that is very well treated during CDISC Define-XML trainings. The next one is during the CDISC European Interchange at the end of April in Berlin. There are still a few places available ...
Hi Jozef, Thanks a lot for…
Hi Jozef,
Thanks a lot for your prompt response! Could you please help me with an example when "Imputation" should be used in ADaM submissions? Should it be used for any type of imputation (e.g. for AVAL when DTYPE is set or for date/time when date/time imputation flags are used)? I did the CDISC Define-XML training and in the provided examples always Computation was used. Even for methods like "AE.AESTDTC, converted to a numeric SAS date. Some events with partial dates are imputed in a conservative manner. If the day component is missing, a value of '01' is used. If both the month and day are missing no imputation is performed as these dates clearly indicate a start prior to the beginning of treatment. There are no events with completely missing start dates."
So I am confused when I should use it.
MethodDef Element Type
I am not an ADaM specialist at all, so I can't help you here.
As your question has nothing to do with P21, my strong suggestion is to join the LinkedIn "CDISC Group" (https://www.linkedin.com/groups/56393/ - it "only" has 26,000 members), and ask your question there. I am sure there are several hundreds of ADaM experts there.
Dear all,
according to the Define-XML specification, the allowable values for "type" in MethodDef Element are "Computation" and "Imputation". The description for type is "Computation is intended to describe an algorithm to populate a value; Imputation is the process of replacing missing data with substitute values."
However, I never saw a Define where type="Imputation" was used (not even in the CDISC examples). Could you please help me in which cases "Imputation" should be used?
Thanks a lot!